Julkaisut 2014

An Increase in Serum 25-Hydroxyvitamin D Concentrations Preceded a Plateau in Type 1 Diabetes Incidence in Finnish Children.
Mäkinen M, Simell V, Mykkänen J, Ilonen J, Veijola R, Hyöty H, Knip M, Simell O, Toppari J, Hermann R
J Clin Endocrinol Metab.
Antibodies to lactobacilli and bifidobacteria in young children with different propensity to develop islet autoimmunity
Talja I, Kubo AL, Veijola R, Knip M, Simell O, Ilonen J, Vähä-Mäkilä M, Sepp E, Mikelsaar M, Utt M, Uibo R
J Immunol Res.
At high risk for early withdrawal: using a cumulative risk model to increase retention in the first year of the TEDDY study
Johnson SB, Lynch KF, Lee HS, Smith L, Baxter J, Lernmark B, Roth R, Simell T, TEDDY Study Group
J Clin Epidemiol
Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study
Lee HS, Burkhardt BR, McLeod W, Smith S, Eberhard C, Lynch K, Hadley D, Rewers M, Simell O, She JX, Hagopian B, Lernmark A, Akolkar B, Ziegler AG, Krischer JP, TEDDY study group
Diabetes Metab Res Rev
Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease
Elding Larsson H, Vehik K, Gesualdo P, Akolkar B, Hagopian W, Krischer J, Lernmark Å, Rewers M, Simell O, She JX, Ziegler A, Haller MJ, TEDDY Study Group
Pediatr Diabetes
Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes
Laitinen OH, Honkanen H, Pakkanen O, Oikarinen S, Hankaniemi MM, Huhtala H, Ruokoranta T, Lecouturier V, André P, Harju R, Virtanen SM, Lehtonen J, Almond JW, Simell T, Simell O, Ilonen J, Veijola R, Knip M, Hyöty H
Diabetes
Diagnostic methods for and clinical pictures of polyomavirus primary infections in children, Finland
Chen T, Tanner L, Simell V, Hedman L, Mäkinen M, Sadeghi M, Veijola R, Hyöty H, Ilonen J, Knip M, Toppari J, Simell O, Söderlund-Venermo M, Hedman K
Emerg Infect Dis.
Factors associated with maternal-reported actions to prevent type 1 diabetes in the first year of the TEDDY study
Smith LB, Lynch KF, Baxter J, Lernmark B, Roth R, Simell T, Johnson SB, TEDDY Study Group
Diabetes Care
Food diversity in infancy and the risk of childhood asthma and allergies
Nwaru BI, Takkinen HM, Kaila M, Erkkola M, Ahonen S, Pekkanen J, Simell O, Veijola R, Ilonen J, Hyöty H, Knip M, Virtanen SM
J Allergy Clin Immunol.
Infant feeding patterns in families with a diabetes history – observations from The Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study
Hummel S, Vehik K, Uusitalo U, McLeod W, Aronsson CA, Frank N, Gesualdo P, Yang J, Norris JM, Virtanen SM, TEDDY Study Group
Public Health Nutr
Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility
Kallionpää H, Elo LL, Laajala E, Mykkänen J, Ricaño-Ponce I, Vaarma M, Laajala TD, Hyöty H, Ilonen J, Veijola R, Simell T, Wijmenga C, Knip M, Lähdesmäki H, Simell O, Lahesmaa R
Diabetes
Maternal dietary fatty acid intake during pregnancy and the risk of preclinical and clinical type 1 diabetes in the offspring
Niinistö S, Takkinen HM, Uusitalo L, Rautanen J, Nevalainen J, Kenward MG, Lumia M, Simell O, Veijola R, Ilonen J, Knip M, Virtanen SM
Br J Nutr.
No association between vitamin D and β-cell autoimmunity in Finnish and Estonian children
Reinert-Hartwall L, Honkanen J, Härkönen T, Ilonen J, Simell O, Peet A, Tillmann V, Lamberg-Allardt C, Virtanen SM, Knip M, Vaarala O, DIABIMMUNE Study Group
Diabetes Metab Res Rev
Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes
Yang J, Lernmark A, Uusitalo UM, Lynch KF, Veijola R, Winkler C, Larsson HE, Rewers M, She JX, Ziegler AG, Simell OG, Hagopian WA, Akolkar B, Krischer JP, Vehik K, the TEDDY Study Group
Int J Obes (Lond)
Risk of pediatric celiac disease according to HLA haplotype and country
Liu E, Lee HS, Aronsson CA, Hagopian WA, Koletzko S, Rewers MJ, Eisenbarth GS, Bingley PJ, Bonifacio E, Simell V, Agardh D, TEDDY Study Group
N Engl J Med
The HLA-B*39 allele increases type 1 diabetes risk conferred by HLA-DRB1*04:04-DQB1*03:02 and HLA-DRB1*08-DQB1*04 class II haplotypes
Mikk ML, Kiviniemi M, Laine AP, Härkönen T, Veijola R, Simell O, Knip M, Ilonen J, Finnish Paediatric Diabetes Register
Hum Immunol.